Saturday, July 12, 2014

News: Hidden Origins of Pulmonary Hypertension Revealed by Network Modeling

In a groundbreaking study, researchers from Brigham and Women's Hospital (BWH) have identified a related family of molecules believed to be a major root cause of pulmonary hypertension, a deadly vascular disease with undefined origins. This is one of the first studies to leverage advanced computational network modeling to decipher the molecular secrets of this complex human disease.

The study is published online June 24, 2014 in The Journal of Clinical Investigation. The senior corresponding author, Stephen Y. Chan, MD, PhD, BWH Divisions of Cardiovascular Medicine and Network Medicine, was a 2010 recipient of PHA's K08 Supplemental Award.

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