Friday, November 22, 2013

Thirty Percent of Sickle Cell Patients Develop Pulmonary Hypertension

Today in Associated Disease Week we highlight sickle cell disease.

Pulmonary hypertension is an increasingly recognized complication of sickle cell disease (SCD). Studies show that approximately 30% of screened adult patients with SCD develop mild PH in adulthood. In 10% of patients, the PH is more severe. Recent autopsy studies also suggest that up to 75% of sickle cell patients show changes in the lung tissue at the time of death, indicating the existence of pulmonary arterial hypertension (PAH).

In the past day, researchers from the sickle cell center at Georgia Regents University announced through a press release that they have found promise with pulmonary hypertension drugs for turning down the inflammation and blood vessel constriction that results from the imbalance of nitric oxide and endothelin. Read the article

Share these resources with the people you know who have sickle cell disease:

PH & Sickle Cell Disease brochure | Conference 2012 session recording | Sickle Cell Association of America

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