Tuesday, January 8, 2013

PH in the News: Disruption of Cellular Signaling Identified in Pulmonary Arterial Hypertension

Impairment of a key signaling cascade in the pulmonary blood vessels plays an important role in pulmonary arterial hypertension (PAH), a Yale study has found.

Recent studies have described the role of the gene apelin in the signaling process that maintains normal pulmonary vascular function. Apelin levels have been found to be significantly reduced in patients with PAH.

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1 comment:

Dawni said...

This maybe the best news for PH patients since Flolan. Also another alternative for lung transplant patients. I hope they will do the trials asap. Especially for pedatrics.